day 1 agenda
| 7th Edition of Innovations and State of the Art in | |
| ALZHEIMER'S & DEMENTIA | |
| on Sep 07-08, 2026 at Paris, France | |
| Day -1(Sep 07, 2026) | |
| Keynote Sessions | |
| 09:00-09:30 | KeynoteTalk: Genetic Therapies for APOE4-Associated Alzheimer’s Diseases |
| Ronald Crystal, Weill Cornell Medicine, USA | |
| 09:30-10:00 | KeynoteTalk: ACE-dependent Alzheimer’s disease (AD) |
| Sergei M. Danilov, University of Illinois, USA | |
| 10:00-10:30 | KeynoteTalk: Glomerular (mesangial) amyloidogenesis in AL (light chain-associated) amyloidosis: Translational studies with implications for further treatment modalities. Similarities with amyloid formation in Alzheimer disease |
| Guillermo A. Herrera, University of South Alabama, USA | |
| Group Photo & Refreshment Break (10:30-10:50) | |
| Session Chairs | |
| Ronald G. Crystal, USA & Donald E. Moss, USA | |
| Technical session-I | |
| Advances in Alzheimer’s and Dementia Research & Neurodegenerative Diseases |
|
| 10:50-11:10 | Relationships among tau, amyloid, neuroinflammation, NMDA receptors and cognitive performance are strongly modulated by sex |
| Anat Biegon, University of Uppsala, Sweden | |
| 11:10-11:30 | Imaging oxidative stress in neurodegenerative disorders with Positron Emission Tomography with [18F]ROStrace |
| Robert H. Mach, University of Pennsylvania, USA | |
| 11:30-11:50 | Prevention and Reversal of Alzheimer's Disease |
| Andrew A. Pieper, Case Western Reserve University, USA | |
| 11:50-12:10 | Slot Available |
| 12:10-12:30 | Moderate-Severe Traumatic Brain Injury May Cause Neurodegeneration in the Early and Late Chronic Stages of Injury |
| Robin Green , University of Toronto, Canada | |
| 12:30-12:50 | Intermittent hypoxia training attenuates brain atrophy in elderly adultswith mild cognitive impairment |
| Xiangrong Shi, University of North Texas Health Science Centre, USA | |
| 12:50-13:10 | Slot Available |
| Lunch Break @ Restaurant (13:10-14:00) | |
| 14:00-14:20 | The Enigma of Brain Iron: From Brain Iron Overload to Functional Iron Deficiency in Neurodegenerative Diseases |
| Levi Sonia, University Vita-Salute San Raffaele , Italy | |
| 14:20-14:40 | Nonhuman Primate Models of Alzheimer’s Disease And Parkinson’sDisease Co-pathologies |
| Jeffrey H. Kordower, Arizona State University, USA | |
| 14:40-15:00 | Slot Available |
| Session Chair | |
| Ebrahim Zandi, USA | |
| Technical session-II | |
| Dementia diagnosis, treatment | |
| & | |
| Vascular Dementia, Aging and Dementia, Risk reduction and prevention | |
| 15:00-15:30 | Plenary Talk: Digital Twins in Clinical Trials for Alzheimer’s Disease |
| Irfan Chaudhuri, Harvard University, USA | |
| 15:30-15:50 | The Traumatic brain injury and the risk of dementia |
| Wendy Lin, University of British Columbia, Canada | |
| 15:50-16:10 | Arterial Tortuosity as a Marker of Cerebrovascular Aging and Dementia Risk |
| Yulin Ge, NYU Grossman School of Medicine, USA | |
| 16:10-16:30 | Slot Available |
| 16:30-16:50 | Stepwise identification of prodromal dementia: testing a practical model for primary care |
| Boaz Levy, University of Massachusetts Boston, USA | |
| 16:50-17:10 | Involvement of Mitochondrial Type 10 17β-Hydroxysteroid Dehydrogenase in the Pathogenesis of Neurodegeneration |
| Xue-Ying He & Song-Yu Yang, NYS Institute for Basic Research in Developmental Disabilities, USA | |
| Refreshment Break(17:10-17:30) | |
| Note: This is a Tentative program, subjects and timings will changes. | |
| Day-1 Concludes | |
day 2 agenda
| Day -2(Sep 08, 2026) | |
| Keynote Sessions | |
| 09:00-09:30 | KeynoteTalk: GABA-A receptor modulating steroids enhance dementia, but antagonists inhibit inflammation and improve memory |
| Torbjörn Bäckström, Umeå University, Sweden | |
| 09:30-10:00 | Cortical neuron dysfunction in AD brain at early-stage without beta-amyloid aggregation |
| Xiu-Ti Hu, Rush University Medical Center, USA | |
| 10:00-10:30 | KeynoteTalk: Acetylcholinesterase inhibitors have anti- neurodegenerative benefits, but high-level CNS-selective acetylcholinesterase inhibition is needed for delaying the onset or preventing Alzheimer’s dementia |
| Donald E. Moss, University of Texas at El Paso, USA | |
| Group Photo & Refreshment Break (10:30-10:50) | |
| Session Chair | |
| Xiu-Ti Hu, USA | |
| Technical session-III | |
| Biomarkers for AD and Dementia, Basic and Translational Research & Genetics in Alzheimer’s and Dementia, Molecular and Cell Biology, Data Science and Artificial Intelligence |
|
| 10:50-11:10 | Long read sequencing in alzheimer’s disease and cerebral amyloid angiopathy |
| Amanda J. Myers, University of Miami, USA | |
| 11:10-11:30 | From Cost-Effective Plasma Biomarker Quantification to Cross-Cohort Machine Learning Translation in Alzheimer’s Disease |
| Ebrahim Zandi, University of Southern California, USA | |
| 11:30-11:50 | Towards a panel of seed amplification assays for the detection of protein pathologies in the CSF of living patients with dementia |
| Magnus Macleod, University College London, UK | |
| 11:50-12:10 | Slot Available |
| 12:10-12:30 | Exploring the role of Aβ-induced membrane damage in tau pathology |
| Katherine R. Sadleir, , Northwestern University, USA | |
| 12:30-12:50 | Development and Validation of Patient and Caregiver-Reported Outcome Measures for Alzheimer’s Disease, Mild Cognitive Impairment, and Dementia: The CI-HI & CICR-HI |
| Charlotte Engebrecht, University of Rochester Center for Health + Technology, USA | |
| 12:50-13:10 | Obtaining personalized predictions from a randomized controlled trial on Alzheimer’s disease |
| Dennis Shen, University of Southern California, USA | |
| 13:10-13:30 | Beyond Plaques and Tangles: Visualizing Early Oxidative Stress in Alzheimer's Disease via a Novel Radiotracer |
| Meagan J McManus, University of Arizona, USA | |
| Lunch Break @ Restaurant (13:30-14:10) | |
| Session Chair | |
| Guillermo A. Herrera, USA | |
| Technical session-IV | |
| Clinical Trials and Therapeutics & AD Drug Development and Animal Models |
|
| 14:10-14:30 | Transcranial Pulse Stimulation for early dementia: A Randomized, Sham-Controlled Safety and Efficacy Study |
| Francesca Pistoia, University of L'Aquila, Italy | |
| 14:30-14:50 | Personalizing Repetitive TMS in Major Depressive Disorder: An EEG?Based dlPFC Sensitivity Index Predicts Clinical and Cognitive Outcomes |
| Li Wan, Anhui Medical University, USA | |
| 14:50-15:10 | Proximity proteomics reveals distinct pE3-Aβ-associated networks in human Alzheimer’s disease hippocampus |
| Alia O. Alia, Rush University Medical Center, USA | |
| 15:10-15:30 | Slot Available |
| 15:30-15:50 | Federated Learning for Early Diagnosis of the Dementia |
| Mohamed Elsersy, Higher Colleges of Technology, UAE | |
| 15:50-16:10 | Tirzepatide Attenuates Neurotoxicity by Suppressing Inflammation, Apoptosis, and Restoring Neurotrophin Expression in an Alzheimer’s Disease-Like Rat Model |
| Sabry Attia, King Saud University, Saudi Arabia | |
| Refreshment Break(16:10-16:30) | |
| Note: This is a Tentative program, subjects and timings will changes. | |
| Day-2 Concludes | |
posters agenda
| Day -1(Sep 07, 2026) | |
| Virtual Tentative Program followed by CET | |
| 10:00-10:20 | 6-microRNA panel predicts amyloid-b status in cognitively normal older adults |
| Joanna M. Williams, University of Otago, NewZealand | |
| 10:20-10:40 | Development of amyloid β (1-42) certified reference material NMIJ CRM 6210-a |
| Kazumi Saikusa, National Metrology Institute of Japan (NMIJ), Japan | |
| 10:40-11:00 | Slot Available |
| 11:00-11:20 | Huntingtin’s N17 region: Post-translational modifications as modulators of protein self-association and membrane interaction |
| Mariana Gallo, University of Parma, Italy | |
| 11:20-11:50 | Keynote Talk: NAP, the investigational drug davunetide, from laboratory discovery to sex-specific cognitive protection in clinical trials |
| Illana Gozes, Tel Aviv University, Israel | |
| 11:50-12:10 | Selective manipulation of aging as a novel treatment for neurodegenerative disorders |
| Ehud Cohen, The Hebrew University School of Medicine, Israel | |
| 12:10-12:30 | Slot Available |
| 12:30-12:50 | Early Linguistic Indicators and Language-Focused Therapies in Alzheimer’s Disease |
| Erika Smeriglio, University of Messina, Italy | |
| 12:50-13:10 | Slot Available |
| 13:10-13:30 | Correction of the APP London (V717I) mutation using an optimized prime editing system. |
| Jacques P. Tremblay, Université Laval, Canada | |
| 13:30-13:50 | Methionine-sulfoxide based active immunization against Alzheimer’s disease |
| Jackob Moskovitz, University of Kansas, USA | |
| 13:50-14:20 | Keynote Talk: Elovanoids: linking nutrition to neuroprotection |
| Nicolas G. Bazan, Neuroscience Center of Excellence, USA | |
| 14:20-14:40 | Spiritual Fitness: The New Dimension In Alzheimer’s Disease Prevention |
| Eve Adler, Alzheimer's Research and Prevention Foundation, USA | |
| 14:40-15:00 | The importance of social relationships in place in Alzheimer’s Disease |
| George Rook, a person living with dementia and co-researcher on several projects, USA | |
| 15:00-15:20 | Slot Available |
| 15:20-15:40 | Establishing two-tier cutoffs for ptau217/A42 ratio in plasma for detection of Alzheimers disease pathology |
| Leslie M Shaw, University of Pennsylvania, USA | |
| 15:40-16:00 | Air pollution risk of Alzheimer in a mouse model of amyloidogenesis is attenuated by modulation of gamma-secretase |
| Caleb E Finch, University of Southern California, USA | |
| Day-1 Concludes | |
| Day -2(Sep 08, 2026) | |
| Virtual Tentative Program followed by CET | |
| 10:00-10:20 | Cultural Perspectives on Virtual delivery of Cognitive Stimulation Therapy for M?ori with Dementia (vCST-M?ori) |
| Tai Kake, University of Auckland, NewZealand | |
| 10:20-10:40 | The therapeutic potential of medicinal cannabis for neurodegenerative diseases – a preclinical perspective |
| Tim Karl, Western Sydney University, Australia | |
| 10:40-11:00 | Slot Available |
| 11:00-11:20 | Revitalizing Mitochondria against Alzheimer’s disease: The Synergistic Effects of a Nutraceutical Combination with urolithin A |
| Dona Pamoda W. Jayatunga, University of Sri Jayewardenepura, Sri Lanka | |
| 11:20-11:50 | Keynote Talk: Restoring neuronal function by restoring the septin cytoskeleton |
| Gerard Griffioen, remynd, Belgium | |
| 11:50-12:10 | Targeting the GSK3β/Nav1.6 protein–protein interaction offers a promising new therapeutic approach for early-stage Alzheimer’s disease |
| Fernanda Laezza, University of Texas Medical Branch, USA | |
| 12:10-12:30 | Non-catalyzed covalent dimerization of amyloid b and implications for Alzheimer’s disease |
| Suren A. Tatulian, University of Central Florida, USA | |
| 12:30-12:50 | Protein disulfide isomerase dissolves and detoxifies oligomeric assemblies of amyloid beta peptide |
| Ken Teter, University of Central Florida, USA | |
| 12:50-13:10 | Molecular Mechanisms Underlying the Inverse Roles of Heme Function in Lung Cancer and Alzheimer’s Disease |
| Li Zhang, University of Texas at Dallas, USA | |
| 13:10-13:30 | Slot Available |
| 13:30-13:50 | Alzheimer’s Is Dynamic – Our Language Has Not Kept Pace: Redefining Diagnosis Through Precision and Human-Centered Staging |
| Lauren P. Brown, The Alzheimer's Experience, USA | |
| 13:50-14:20 | Keynote Talk: Systems Thinking |
| Michael Fossel, Michigan State University, USA | |
| 14:20-14:40 | Identification of novel shared antibodies and infectious disease associations in Alzheimer’s disease |
| Mark Hicar, University at Buffalo, USA | |
| 14:40-15:00 | Slot Available |
| 15:00-15:20 | Asymmetric Cerebral Hypoperfusion Drives Regional Blood Brain Barrier Permeability in a Vascular Dementia Model |
| Zhen Xu, The University of Texas Health Science Center at Houston, USA | |
The program for this session is currently being updated to accommodate recently received abstracts and ongoing scientific scheduling.
Full session details will be announced soon.