day 1 agenda
| 7th Edition of Innovations and State of the Art in ALZHEIMER'S & DEMENTIA on Sep 07-08, 2026 at Paris, France |
|
| Day -1(Sep 07, 2026) | |
| Meeting Hall: Paris 1 | |
| Registrations Open(08:30-08:50) | |
Moderator Meagan J McManus, USA |
|
| Welocme Remarks(08:50:09:10) | |
| Keynote Sessions | |
| 09:10- 09:40 | KeynoteTalk: Genetic Therapies for APOE4-Associated Alzheimer’s Diseases |
| Ronald Crystal,Weill Cornell Medicine,USA | |
| 09:40-10:10 | KeynoteTalk: ACE-dependent Alzheimer’s disease (AD) |
| Sergei M. Danilov,University of Illinois,USA | |
| 10:10-10:40 | KeynoteTalk: Glomerular (mesangial) amyloidogenesis in AL (light chain-associated) amyloidosis: Translational studies with implications for further treatment modalities. Similarities with amyloid formation in Alzheimer disease |
| Guillermo A. Herrera,University of South Alabama,USA | |
| Group Photo & Refreshment Break (10:40-11:00) | |
| Session Chairs | |
| Ronald G. Crystal, USA & Guillermo A. Herrera, USA | |
| Technical session-I | |
| Advances in Alzheimer’s and Dementia Research & Neurodegenerative Diseases |
|
| 11:00-11:20 | Relationships among tau, amyloid, neuroinflammation, NMDA receptors and cognitive performance are strongly modulated by sex |
| Anat Biegon, University of Uppsala, Sweden | |
| 11:20-11:40 | Moderate-Severe Traumatic Brain Injury May Cause Neurodegeneration in the Early and Late Chronic Stages of Injury |
| Robin Green,University of Toronto, Canada | |
| 11:40-12:00 | The Enigma of Brain Iron: From Brain Iron Overload to Functional Iron Deficiency in Neurodegenerative Diseases |
| Levi Sonia,University Vita-Salute San Raffaele, Italy | |
| 12:00-12:20 | Intermittent hypoxia training attenuates brain atrophy in elderly adultswith mild cognitive impairment |
| Xiangrong Shi, University of North Texas Health Science Centre, USA | |
| 12:20-12:40 | Nonhuman Primate Models of Alzheimer’s Disease And Parkinson’sDisease Co-pathologies |
| Jeffrey H. Kordower, Arizona State University, USA | |
| 12:40-13:00 | Imaging oxidative stress in neurodegenerative disorders with Positron Emission Tomography with [18F]ROStrace |
| Robert H. Mach,University of Pennsylvania, USA | |
| 13:00-13:20 | Beyond Plaques and Tangles: Visualizing Early Oxidative Stress in Alzheimer's Disease via a Novel Radiotracer |
| Meagan J McManus,University of Arizona,USA | |
| Lunch Break @ Restaurant (13:20-14:10) | |
| Session Chair | |
| Ebrahim Zandi, USA | |
| Technical session-II | |
| Vascular Dementia, Aging and Dementia, Risk reduction and prevention | |
| 14:10-14:40 | Plenary Talk: Digital Twins in Clinical Trials for Alzheimer’s Disease |
| Irfan Chaudhuri, Harvard University, USA | |
| 14:40-15:00 | The Traumatic brain injury and the risk of dementia |
| Wendy Lin, University of British Columbia, Canada | |
| 15:00-15:20 | Arterial Tortuosity as a Marker of Cerebrovascular Aging and Dementia Risk |
| Yulin Ge, NYU Grossman School of Medicine, USA | |
| 15:20-15:40 | Stepwise identification of prodromal dementia: testing a practical model for primary care |
| Boaz Levy, University of Massachusetts Boston, USA | |
| 15:40-16:00 | Involvement of Mitochondrial Type 10 17β-Hydroxysteroid Dehydrogenase in the Pathogenesis of Neurodegeneration |
| Xue-Ying He & Song-Yu Yang, NYS Institute for Basic Research in Developmental Disabilities, USA | |
| PP-1 | PASSCOG: Early Diagnosis of Alzheimer's Disease in Outpatient Settings |
| Blanchard Apolline & Gagliardi Geoffroy, Aloïs Association, France | |
| Refreshment Break(16:20-16:30) | |
| Day-1 Concludes | |
day 2 agenda
| Day -2(Sep 08, 2026) | |
| Meeting Hall: Paris 1 | |
| Registrations Open(08:30-08:50) | |
| Moderator TBA |
|
| Welocme Remarks(08:50:09:00) | |
| Keynote Sessions | |
| 09:00-09:30 | KeynoteTalk: GABA-A receptor modulating steroids enhance dementia, but antagonists inhibit inflammation and improve memory |
| Torbjörn Bäckström, Umeå University, Sweden | |
| 09:30-10:00 | KeynoteTalk: Acetylcholinesterase inhibitors have anti- neurodegenerative benefits, but high-level CNS-selective acetylcholinesterase inhibition is needed for delaying the onset or preventing Alzheimer’s dementia |
| Donald E. Moss, University of Texas at El Paso, USA | |
| 10:00-10:30 | KeynoteTalk: Cortical neuron dysfunction in AD brain at early-stage without beta-amyloid aggregation |
| Xiu-Ti Hu, Rush University Medical Center, USA | |
| Group Photo & Refreshment Break (10:30-10:50) | |
| Session Chairs | |
| Xiu-Ti Hu, USA & Donald E. Moss, USA | |
| Technical session-III | |
| Biomarkers for AD and Dementia, Basic and Translational Research & Genetics in Alzheimer’s and Dementia, Molecular and Cell Biology, Data Science and Artificial Intelligence |
|
| 10:50-11:10 | Long read sequencing in alzheimer’s disease and cerebral amyloid angiopathy |
| Amanda J. Myers, University of Miami, USA | |
| 11:10-11:30 | From Cost-Effective Plasma Biomarker Quantification to Cross-Cohort Machine Learning Translation in Alzheimer’s Disease |
| Ebrahim Zandi, University of Southern California, USA | |
| 11:30-11:50 | Towards a panel of seed amplification assays for the detection of protein pathologies in the CSF of living patients with dementia |
| Magnus Macleod, University College London, United Kingdom | |
| 11:50-12:10 | Exploring the role of Aβ-induced membrane damage in tau pathology |
| Katherine R. Sadleir, Northwestern University, USA | |
| 12:10-12:30 | Development and Validation of Patient and Caregiver-Reported Outcome Measures for Alzheimer’s Disease, Mild Cognitive Impairment, and Dementia: The CI-HI & CICR-HI |
| Charlotte Engebrecht, University of Rochester Center for Health + Technology, USA | |
| 12:30-12:50 | Transcranial Pulse Stimulation for early dementia: A Randomized, Sham-Controlled Safety and Efficacy Study |
| Francesca Pistoia, University of L'Aquila, Italy | |
| 12:50-13:10 | Personalizing Repetitive TMS in Major Depressive Disorder: An EEG?Based dlPFC Sensitivity Index Predicts Clinical and Cognitive Outcomes |
| Li Wan, Anhui Medical University, USA | |
| Lunch Break @ Restaurant (13:10-14:00) | |
posters agenda
| Day -1(Sep 07, 2026) | |
| Virtual Program followed by CET(Paris Time) | |
| 13:10-13:30 | Keynote Talk: Systems Thinking |
| Michael Fossel, Michigan State University, USA | |
| 13:30-13:50 | The importance of social relationships in place in Alzheimer’s Disease |
| George Rook, a person living with dementia and co-researcher on several projects, USA | |
| 13:50-14:20 | Establishing two-tier cutoffs for ptau217/A42 ratio in plasma for detection of Alzheimers disease pathology |
| Leslie M Shaw, University of Pennsylvania, USA | |
| 14:20-14:40 | Keynote Talk: Elovanoids: linking nutrition to neuroprotection |
| Nicolas G. Bazan,Neuroscience Center of Excellence, USA | |
| 14:40-15:00 | Methionine-sulfoxide based active immunization against Alzheimer’s disease |
| Jackob Moskovitz, University of Kansas, USA | |
| 15:00-15:20 | Spiritual Fitness: The New Dimension In Alzheimer’s Disease Prevention |
| Eve Adler, Alzheimer's Research and Prevention Foundation, USA | |
| 15:20-15:40 | Alzheimer’s disease: Amyloid beta switch from physiology to pathology and novel prevention and treatment approaches |
| Yuri Lyubchenko, University of Nebraska Medical Center, USA | |
| 15:40-16:00 | From amyloid plaques to tau neurofibrillary tangles: Connecting the dots in Alzheimer’s disease through GPC4 |
| Brandon B. Holmes, University of California, USA | |
| 16:00-16:20 | Treatment of bioenergetic and redox impairment in neurons promotes clearance of Aβ and tau aggregates, lowers oxidative nitration and promotes synapse formation |
| Gregory J. Brewer, University of Califormia, USA | |
| 16:20-16:40 | Air pollution risk of Alzheimer in a mouse model of amyloidogenesis is attenuated by modulation of gamma-secretase |
| Caleb E Finch, University of Southern California, USA | |
| 16:40-17:00 | Combination treatment targeting upstream mechanisms of Alzheimer’s disease reduces biomarkers of disease and promotes synapse formation |
| Svara Shah, University of California Irvine, USA | |
| Day-1 Concludes | |
| Day -2(Sep 08, 2026) | |
| Virtual Program followed by CET(Paris Time) | |
| 08:30-08:50 | 6-microRNA panel predicts amyloid- β status in cognitively normal older adults |
| Joanna M. Williams, University of Otago, NewZealand | |
| 08:50-09:10 | Cultural Perspectives on Virtual delivery of Cognitive Stimulation Therapy for M?ori with Dementia (vCST-M?ori) |
| Tai Kake, University of Auckland, NewZealand | |
| 09:10-09:30 | The therapeutic potential of medicinal cannabis for neurodegenerative diseases – a preclinical perspective |
| Tim Karl, Western Sydney University, Australia | |
| 09:30-09:50 | Development of amyloid β (1-42) certified reference material NMIJ CRM 6210-a |
| Kazumi Saikusa, National Metrology Institute of Japan (NMIJ), Japan | |
| 09:50-10:20 | Keynote Talk: NAP, the investigational drug davunetide, from laboratory discovery to sex-specific cognitive protection in clinical trials |
| Illana Gozes, Tel Aviv University, Israel | |
| 10:20-10:40 | Revitalizing Mitochondria against Alzheimer’s disease: The Synergistic Effects of a Nutraceutical Combination with urolithin A |
| Dona Pamoda W. Jayatunga, University of Sri Jayewardenepura, Sri Lanka | |
| 10:40-11:00 | Early Linguistic Indicators and Language-Focused Therapies in Alzheimer’s Disease |
| Erika Smeriglio, University of Messina, Italy | |
| 11:00-11:20 | Insights into Alzheimer’s Disease from Drosophila Models: Lessons Learned and Future Directions |
| Ann-Christin Brorsson, Linköping University, Sweden | |
| 11:20-11:50 | Keynote Talk: Restoring neuronal function by restoring the septin cytoskeleton |
| Gerard Griffioen, remynd, Belgium | |
| 11:50-12:10 | Huntingtin’s N17 region: Post-translational modifications as modulators of protein self-association and membrane interaction |
| Mariana Gallo, University of Parma, Italy | |
| 12:10-12:30 | Selective manipulation of aging as a novel treatment for neurodegenerative disorders |
| Ehud Cohen, The Hebrew University School of Medicine, Israel | |
| 12:30-12:50 | ‘This Is a Completely Changed Landscape’: Older Men’s Experiences of Caring for a Spouse with Dementia |
| Olga Asrun Stefansdottir, University of Akureyri, Iceland | |
| 12:50-13:10 | AI-Driven Insights from Single-Cell Transcriptomics in Alzheimer’s Disease: Emerging Biomarkers and Therapeutic Targets |
| Prachi Srivastava, Amity University, India | |
| 13:10-13:30 | Correction of the APP London (V717I) mutation using an optimized prime editing system |
| Jacques P. Tremblay, Université Laval, Canada | |
| 13:30-13:50 | Non-catalyzed covalent dimerization of amyloid β and implications for Alzheimer’s disease |
| Suren A. Tatulian, University of Central Florida, USA | |
| 13:50-14:10 | Identification of novel shared antibodies and infectious disease associations in Alzheimer’s disease |
| Mark Hicar, University at Buffalo, USA | |
| 14:10-14:30 | Protein disulfide isomerase dissolves and detoxifies oligomeric assemblies of amyloid beta peptide |
| Ken Teter, University of Central Florida, USA | |
| 14:30-14:50 | Molecular Mechanisms Underlying the Inverse Roles of Heme Function in Lung Cancer and Alzheimer’s Disease |
| Li Zhang, Download
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